October 26, 2017
Yesterday, the Journal of the American Medical Association (JAMA) Psychiatry published an article by researchers from the Centre of Addiction and Mental Health (CAMH), demonstrating that Alzheimer’s patients have reduced brain plasticity in the frontal lobes, which may underlie an impairment in working memory.
Institute grantee Dr. Tarek Rajji, Chief of the Geriatric Psychiatry Division at CAMH, is the senior author of the study. It involved 32 Alzheimer’s disease (AD) patients who underwent brain stimulation, and had their scalp electroencephalography (EEG) recorded to measure the evoked brain response. Researchers used changes in the recorded brain signal as a measure of neuroplasticity.
He will next focus on using brain stimulation as a tool to modulate brain plasticity, and potentially improve working memory in patients with AD. Dr. Rajji was funded through the Rapid Response 2012 program.
Read more about Dr. Rajji’s Institute-funded work here.
Read the press release from CAMH here.