2014 Targeted Diseases: FTD/PSP

The goal of the Targeted Diseases program is to provide targeted support for high impact, translational research in frontotemporal dementia (FTD) and progressive supranuclear palsy (PSP).

Funding and Eligibility

The Institute will commit up to $1.35 million to this program. Per project, funding can range from $50,000 to $150,000 per year over 1 to 3 years to a maximum of $450,000.

Proposed projects must be translational research and fall into one of these two categories to be eligible for funding:

  • Preclinical to Phase II development of a therapeutic for FTD or PSP
  • Development of tools that help accelerate development of therapeutics for FTD or PSP

Research in other overlapping tauopathies, such as corticobasal degeneration, is not supported at this time.

Institute definitions:

  • Translational: Applied research towards developing therapeutics for the prevention and/or treatment of human disease. For example, for small molecule drug development, this includes target validation to Phase II clinical trials.
  • Therapeutic: A pharmacological approach (including small molecules, biologics, cell therapies and vaccines, including drug repositioning and repurposing), medical device, surgical intervention, magnetic or electrical brain stimulation, but not complementary approaches such as exercise, acupuncture, foods, or dietary or nutritional supplements. Therapeutics can be for symptomatic relief, disease modification, or prevention.
  • Tool: Some examples are animal models, imaging techniques or reagents, biomarkers and diagnostics.

The program is open to researchers at or above the level of postdoctoral fellow or equivalent from registered charitable institutions in Canada.

Application Process

There are two stages to the application process: Letters of Intent and Proposals. An application for the Targeted Diseases program requires a Letter of Intent due by Friday, June 6, 2014 at 2:00 p.m. EDT. Applicants with high potential projects will be notified of Proposal invitations by late July 2014. Proposal instructions and feedback from our scientific review committee will be forwarded along with the invitation.

For more details about this request for applications, please click here.

To print out a paper reference of the Letter of Intent, please click here.

A sample of the Proposal template is available by clicking here. Please note that the format and questions in the Proposal template are subject to change before the deadline so the template should be used only as an indicator of the expectations at the Proposal stage.

The Institute welcomes inquiries about this request for applications or any of our other funding opportunities. We would be pleased to hear from you at either neuro@weston.ca or 416-935-4056