Novel Biomarkers 2017

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Neurodegenerative diseases of aging are among the least understood and most undertreated diseases today. If ignored, the social and economic costs of managing these diseases will continue to rise. Meeting these challenges requires pioneering approaches to accelerating treatments.

The Novel Biomarkers 2017 program supports high-risk, high-reward, translational research projects in the UK and Ireland that are testing novel biomarkers in clinical samples/data or patients.


Program Overview

Refer to the Program Details for more information.

Goal:   To provide funding for testing of understudied and/or underfunded biomarkers in clinical samples/data or patients, in order to accelerate the development of therapeutics for neurodegenerative diseases of aging.

Funding:   Up to £333,000 (projects based in the UK) or €390,000 (projects based in Ireland) is available per project, over up to 3 years.

Applicant eligibility:   Eligible Principal Applicants must be at or above the level of Lecturer (Assistant Professor) and hold an appointment at the institution from which they are applying. Each applicant may submit one LOI as Principal Applicant, and may appear as a Co-Applicant or Collaborator on an unlimited number of applications.

Eligible Principal Applicants must be either a UK-based researcher working in the UK at least 30% of the time, or an Ireland-based researcher working in Ireland at least 30% of the time.

Institutions must be either a UK-registered charity or be registered with the Charities Regulatory Authority in Ireland. The Institute may also be able to accept applications from qualified institutions in Ireland or the UK meeting the public benefit requirement towards research in neurodegenerative diseases of aging; please contact us before applying.

Disease scope:   All the Institute’s neurodegenerative diseases of aging are covered by this program (see Funding Overview).

Biomarker eligibility:  

  • To be considered novel, biomarkers should be underfunded and/or less studied.
  • Biomarkers should be for disease diagnosis, prognosis, for stratification to clinical trials, or to predict response to therapies.
  • Biomarkers should measure pathology of the disease (e.g., fluid, imaging or tissue biopsy derived biomarkers), and not be based on cognitive, neuropsychological or behavioural phenotypes.
  • Biomarkers should have pilot data to justify testing in clinical samples/data or patients.
  • Genetic determinants and predispositions are not in scope.
  • Biomarker discovery and unbiased screening approaches are not in scope.

The Institute encourages applicants to contact us with any questions regarding this program, including whether a potential idea is in scope.

Application Process:   There are two stages to the application process, Letters of Intent (LOI) and Proposals. An application requires the submission of an LOI which will be reviewed by our scientific review committee. Applicants with high potential projects will be invited to submit a Proposal; instructions will be forwarded along with the invitation in June 2017.

Request for Applications (RFA)

Program Details

Letter of Intent (LOI) sample

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Important Dates*

Letter of Intent deadline:    Wednesday, 10 May 2017, 4:00pm BST

Proposal deadline:                 Friday, 7 September 2017, 4:00pm BST (by invite only)

Award notification:                November 2017

*Dates may change


Program Information Webinar

The Institute will hold two online Program Information Webinars to provide further details on the program and application process, with an opportunity to ask questions.

Information Webinar #1           Tuesday, 31 January 2017, 3:00pm GMT

Information Webinar #2           Thursday, 23 March 2017, 3:00pm GMT                  Register to attend here.

NB: both sessions will include the same information.

 


The Institute welcomes inquiries about this program or any of our other funding opportunities. Contact us at neuro@weston.ca or +1 416-935-4056.