Development of trehalose as a disease-modifying treatment for Parkinson’s disease

2012  -  Toronto, ON, CA


University Health Network at the Toronto Western Research Institute

Project description

We will identify blood and brain levels of trehalose associated with efficacy in an alpha-synuclein model of PD and define dosing strategies to translate these levels to non-human primates. This administration strategy will then be used to assess efficacy of trehalose in an alpha-synuclein-based non-human primate model of PD.