Advisor Fellows 2016

This list does not reflect all upcoming awardees. The awardees are listed once all documents have been finalized.


Pharmacodynamic endpoints for MW151, a novel small molecule attenuator of dysregulated proinflammatory cytokine production

Grantees: Dr. David Braun

Supervising Advisor: Dr. Linda Van Edlik Project Summary: Alzheimer’s disease (AD) is one of the largest global public health crises facing us today, and is predicted to increase dramatically...

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Genetic and environmental influences on early AD biomarkers: a twin approach

Grantees: Dr. Anouk den Braber

Supervising Advisor: Dr. Philip Scheltens Project Summary: Alzheimer’s disease (AD) is an age related neurodegenerative disorder characterized by progressive neuronal loss, and at this stage has no effective treatment....

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Preclinical trajectory of AD: Interactions between APOE gene dose & biomarkers

Grantees: Valentina Ghisays

Supervising Advisor: Dr. Pierre Tariot Project Summary: In the current proposal we seek to evaluate neuroimaging data from the longstanding NIA-supported prospective cohort study (RO1 AG031581, Reiman PI) in...

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Actions of Nuclear Receptors on TREM2+ myeloid cells and in microglia in the AD brain

Grantees: Dr. Miguel Moutinho

Supervising Advisor: Dr. Gary Landreth Project Summary: The Alzheimer’s disease (AD) brain is characterized by an inflammatory environment supported by brain immune cells, which is thought to be a...

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f-MRI study to elucidate mechanism of function of Deep Brain Stimulation (DBS) in Parkinson disease

Grantees: Dr. Manish Ranjan

Supervising Advisor: Dr. Andres Lozano Project Summary: Deep Brain Stimulation (DBS) is proven to be an effective therapy in appropriately selected Parkinson’s disease (PD) patients. Though the DBS is...

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Targeting the Tau-Fyn Interaction in Alzheimer’s Disease

Grantees: Dr. Travis Rush

Supervising Advisor: Dr. Erik Roberson Project Summary: Alzheimer’s disease (AD) affects more than 5 million Americans and is expected to affect 13 million by 2050. Current treatments provide very...

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Role of somatic mitochondrial DNA mutations in vulnerability to α-synuclein toxicity

Grantees: Dr. Janaina Espinosa Teixeira

Supervising Advisor: Dr. David Simon Project Summary The incidence of Parkinson’s disease (PD) rises dramatically with age, but the mechanisms linking aging and PD are unclear. We and others...

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Diagnosing delirium in dementia: the role of an innovative bedside EEG monitor

Grantees: Dr. Viona J.M. Wijnen

Supervising Advisor: Dr. Pim van Gool Project Summary: Delirium, also known as acute confusional state, poses unique challenges in patients with cognitive impairment or clinically manifest dementia. It causes...

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Optimization of Nigrostriatal Degeneration in the α-synuclein preformed fibril Rat Model

Grantees: Joseph Patterson

Supervising Advisor: Dr. Caryl Sortwell Project Summary The hallmarks of Parkinson’s disease (PD) are motor impairments, progressive degeneration of the nigrostriatal dopamine neurons, and the accumulation of inclusions containing...

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