Professor Nick Fox

Professor Nick Fox is currently Professor of Neurology and Director of the Dementia Research Center at the Institute of Neurology, University College London and Honorary Consultant Neurologist at the National Hospital for Neurology and Neurosurgery.

Professor Fox is one of the world’s leaders in neuroimaging whose pioneering work in the development and application of magnetic resonance imaging (MRI) methods has had an enormous impact on the detection, diagnosis and monitoring of progression in cognitive disorders and neurodegenerative dementias. His methods for quantifying brain volume change from serial magnetic resonance imaging (MRI) enabled earlier detection of neurodegeneration and more accurate diagnosis. He showed using serial MRI that hippocampal and global cerebral atrophy were established and accelerating several years before the development of symptoms in Alzheimer’s disease (AD). This work offered the possibility of treating the disease earlier and paved the way for trials in preclinical AD. Professor Fox has also been involved in the use of automated measures of cerebral atrophy derived from serial MRI to assess treatment efficacy and disease-modifying potential of novel therapies. In fact, the tools he has developed transformed the field and become the academic and industry standard for tracking response to therapy in AD clinical trials.

Professor Fox has published over 400 papers, 350 of which in the past 15 years, in leading peer-reviewed journals, and was named “most highly cited” researcher by Thomson Reuters (top 1% of global citations) in 2015 and 2016. He has also earned numerous prestigious awards throughout his career, such as the NIHR Senior Investigator Award and the Alzforum Mensch Award. Professor Fox currently holds leadership positions in a number of organizations such as the Alzheimer’s Disease Neuroimaging Initiative, the Alzheimer’s Society UK Research Strategy Council, the UCL Dementia Strategy Board, among many others. He has also had previous appointments with the Alzheimer’s Imaging Consortium, the NIA/NIH initiative on imaging in MCI and AD, the Alzheimer’s Research UK, the Alzheimer’s Research Forum, and the UK Prime Minister’s Research Champions Group, to name a few.

Professor Fox graduated with 1st Class Honours in Physics and Physiology from Cambridge University. He subsequently obtained a degree in medicine from London University and then specialized in cognitive neurology. Since 1993, he has held Research Fellowships from the Alzheimer’s Society and the Medical Research Council (MRC).

Professor Nick Fox Grants