Dr. Yu Tian Wang

Professor, University of British Columbia

Research in Dr. Yu Tian Wang’s laboratory has been on understanding the mechanisms controlling synaptic transmission in the brain, and the dysfunction of these mechanisms in the pathogenesis of brain disorders such as learning and memory deficits, epilepsy, stroke, and aging brain diseases including Alzheimer’s disease (AD) and Parkinson’s Disease (PD).  Dr. Wang and colleagues have made significant impacts on elucidating the molecular mechanisms underlying brain function under physiological and pathological conditions.  He has studied the roles of synaptic transmission and synaptic plasticity in normal brain functions such as learning and memory (Nature, 1994, 1997, 2000; Science 2004; PNAS 2010) and in the pathogenesis of brain disorders including epilepsy (Nature Genetics 2002), drug addiction (Science 2005) and neurodegeneration (Science 2002, Nature Medicine 2009; Nature Neuroscience 2014). These studies have led to the identification of a number of novel targets upon which new therapeutics may be developed for slowing down memory deficits in brain disorders such as dementia and AD, preventing relapse of abusive drugs, and reducing brain cell loss following acute brain insults such as stroke, and in chronic neurodegenerative diseases such as AD and PD.

Dr. Yu Tian Wang Grants