Dr. Haakon Nygaard

Assistant Professor, University of British Columbia

Dr. Nygaard is an Assistant Professor in the Division of Neurology, and the Charles E. Fipke Professor of Alzheimer’s Research at the University of British Columbia. He completed his residency and chief residency in Neurology at Yale, with board certification in Neurology and Behavioral Neurology/Neuropsychiatry. He entered the Investigative Medicine PhD program at Yale University after completion of his neurology training, focusing on beta amyloid signaling and neuronal network dysfunction in models of Alzheimer’s Disease. He was part of the group characterizing prion protein as a major functional receptor for amyloid in Alzheimer’s disease. He assumed a faculty position as an Assistant Professor in the Department of Neurology at Yale University immediately following PhD defense. While at Yale, he maintained a research laboratory, while co-founding and co-directing Yale’s memory clinic and behavioral neurology fellowship program.

His major scientific interest is in translational neuroscience related to frontotemporal dementia and Alzheimer’s disease, with the goal of bringing new therapeutic compounds from the lab to the clinic.  In addition to the current project in FTD, he is one of 3 PIs on a large NIH-funded translational neuroscience project repurposing the cancer drug saracatinib, a Src family kinase inhibitor, for use in Alzheimer’s, now enrolling in a Phase 2a trial in the US and Canada. He is also the PI on an ongoing project to use ketones as an alternative fuel in Alzheimer’s disease, and modeling circadian rhythms in this disorder.

Dr. Haakon Nygaard Grants