Dr. David Kaplan

Senior Scientist, The Hospital for Sick Children
Head, James Fund Laboratories for Neuroblastoma Research
Professor, University of Toronto


kaplanDavid Kaplan received his BA from Clark University in Worcester, MA, in 1978, and his PhD from Harvard University in Cambridge, MA in 1987. His PhD thesis work at the Dana-Farber Cancer Institute identified PI-3 kinase, a protein important in the growth and survival of many cells in the body. Dr. Kaplan performed his post-doctoral studies at the University of California, San Francisco with Dr. Harold Varmus, studying how growth factors induce their effects in our cells.
In 1990, Dr. Kaplan established a laboratory at the National Cancer Institute in Frederick, MD where he identified Trk as the receptor for nerve growth factor, an important protein that promotes the survival and growth of nerve cells. In 1996, Dr. Kaplan relocated his laboratory to the Montreal Neurological Institute at McGill where he was a professor in the Department of Neurology and Neurosurgery, research head of the Brain Tumour Research Centre, and William Feindel Chair in Neuro-oncology.
In 2002, he became a senior scientist at The Hospital for Sick Children and professor, Department of Molecular Genetics at the University of Toronto. He holds a Canada Research Chair in Cancer and Neuroscience.
His laboratory focuses upon examining how neurodegeneration arises and can be prevented, how stem cells build the brain, on developing drugs to mobilize our stem cells to repair injuries and degeneration, and discovering new drugs to treat brain and childhood cancers.

Dr. David Kaplan Grants