Dr. Jeffrey Rothstein

Jeffrey RothsteinDr. Jeffrey D. Rothstein is the Professor of Neurology and Neuroscience at John Hopkins University, as well as the John W. Griffin Director for the Brain Science Institute (BSi). In 2000 he organized the Robert Packard Center for ALS Research at Johns Hopkins and serves as Director. This is the first multi-Institutional, Multi-National collaborative academic organization devoted toward understanding the cause of ALS and translating the information into new drug and cell based therapies.

Dr. Rothstein studies ALS pathophysiology, basic and disease related astrocyte/oligodendroglial biology and therapy discovery. He has received and/or submitted almost a dozen patents applications based on his research. It was Dr. Rothstein’s research on ALS pathogenesis that led to the first successful, FDA approved drug to alter neurodegeneration in ALS. His work on glutamate transporters and astroglial dysfunction was the first evidence that glial dysfunction could contribute to and accelerate neurodegenerative disease.

Dr. Rothstein has received numerous awards including the Sheila Essay award, the Diamond Award for ALS Research, the Lois Pope Foundation Award for Medical Research, and The Landa Foundation Lectureship.

Dr. Rothstein received a Ph.D. in physiology and biophysics from the University of Illinois Health Sciences Center and a medical degree from the University of Illinois College of Medicine. He completed an internship at the University of North Carolina Memorial Hospital before joining Johns Hopkins for his residency. While at Johns Hopkins, he became chief resident in neurology and completed his fellowship in neuromuscular disease.