Canada: ALS 2016

*The deadline for submitting applications to the Canada: ALS 2016 program has now passed*

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by rapid and progressive degeneration of upper and lower motor neurons, resulting in paralysis and death. There are currently 2,500-3,000 Canadians living with ALS, and there is no cure or effective treatment. The goal of the Canada: ALS 2016 program is to provide targeted support for outstanding translational research that accelerates the development of safe and effective therapies for ALS.

Proposed projects may relate to any disease; however, the basis for selection will be on the potential impact of the project on ALS. Applicants may submit projects that fall within the scope of the Weston Brain Institute’s Rapid Response and/or Transformational Research programs. More information can be found below and in the Program Details.

Request for Applications (RFA)

 Program Details

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Funding and Eligibility

Applicants may apply to both the Canada: ALS 2016 Rapid Response program and Canada: ALS 2016 Transformational Research program. The eligibility and submission criteria are listed below. Applicants must be from institutions that are Canadian Revenue Agency-qualified donees located in Canada.

Canada: ALS 2016 Rapid Response –  Seed funding for novel, high-risk, high-reward projects

  • Projects may request up to $150,000 over up to 18 months.
  • Preliminary data is optional.
  • Principal Applicants must be at the level of Postdoctoral Fellow or higher.
  • Each applicant may submit one Rapid Response application as either the Principal Applicant or the Administrative Supervisor; however, applicants can appear as Co-Applicants or Collaborators on any number of LOIs.

Canada: ALS 2016 Transformational Research –  Larger, longer grants that significantly advance preclinical research

  • Projects may request up to $1,500,000 over up to 3 years.
  • Must have excellent preliminary data.
  • Principal Applicants must be at the level of Assistant Professor or higher. Collaborators must be at the Postdoctoral level or above. Applicants may appear in any role on any number of LOIs.
  • Applicants may submit more than one Transformational Research application.

Development scope

Proposed projects must be translational research and must fall into one of two categories:

1. Development of a therapeutic – For example drugs (including small molecules, biologics, cell therapies and vaccines), medical devices, or surgical interventions.

2. Development of tools that help accelerate development of therapeutics – For example animal models, imaging techniques or reagents, biomarkers and diagnostics.

Disease scope

Proposed projects may relate to any disease; however, the basis for selection will be on the potential impact on amyotrophic lateral sclerosis (ALS). Projects focusing on other neurodegenerative diseases of aging should refer to the Institute’s other funding opportunities.

Please refer to the Program Details for more information on funding and eligibility.

Important Dates

Program Information Session:        Tuesday, March 22nd, 2016, 2:00pm EDT Register here

Letter of Intent Deadline:                  Tuesday, April 19th, 2016, 2:00pm EDT

Proposal Deadline:                              Monday, August 15th, 2016, 2:00pm EDT

Anticipated award notification:      October 2016

Notes: all program dates are subject to change.

Application Process

There are two stages to the application process:

  1. Letters of Intent (LOI)
  2. Proposals

An application for the Canada: ALS 2016 program requires a Letter of Intent submitted through our online system. Applicants with high potential projects will be invited to submit a Proposal.

Letter of Intent sample template – ALS 2016 Rapid Response

Letter of Intent sample template – ALS 2016 Transformational Research

Program Information Session

The Weston Brain Institute will be holding an online Program Information Session for this funding opportunity on Tuesday, March 22nd at 2:00pm EDT. This session will provide you with comprehensive information on the application process and an opportunity for open questions.

Register here

The Institute welcomes inquiries about the Canada: ALS 2016 Program or any of our other funding programs to or 416-935-4056.