May 3, 2017
Weston Brain Institute grantees have made history as they used focused ultrasound (FUS) to safely and non-invasively breach the blood-brain barrier (BBB) temporarily in patients with Alzheimer’s disease (AD) in a clinical trial. This represents an enormous step in developing a new way of treating AD.
In 2013 Dr. Kullervo Hynynen and his colleague Dr. Isabelle Aubert from Sunnybrook Research Institute received funding from our Transformational Research program to develop a focused ultrasound system tailored to opening the blood-brain barrier in humans. An overview of this work can be found here.
In November 2015, Dr. Hynynen and colleagues successfully and safely opened the BBB non-invasively for the first time in a brain cancer patient. The current trial is the first time the BBB has been opened in patients with Alzheimer’s disease.
More information, including a press release on the recent trial, can be found here.
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