Transformational Research 2015

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Neurodegenerative Diseases of Aging

The prevalence of neurodegenerative diseases of aging is high and growing rapidly. This Program aims to support innovative ideas that can advance the development of scientific breakthroughs to accelerate the creation of safe, effective treatments for these diseases. The Program will support world-class projects with excellent preliminary data and significant potential to accelerate the development of therapeutics to treat one or more neurodegenerative diseases of aging.

Funding and Eligibility

Applicants can request a total of $400,000 to $1,500,000 over up to 3 years per project.

Proposed projects must be translational research in neurodegenerative diseases of aging and fall into one of two categories to be eligible for funding:

    1. Preclinical development of a therapeutic.  For example, drugs (including small molecules, biologics, cell therapies and vaccines), medical devices or surgical intervention
    2. Development of tools that help accelerate development of therapeutics.  For example, animal models, imaging techniques or reagents, biomarkers, and diagnostics

 Application Process

Program Information Session:        Tuesday, February 3, 2015, 1:00 p.m. EST
Letter of Intent (LOI) Deadline:       Tuesday, March 3, 2015, 2:00 p.m. EST
Proposal Deadline:                                Tuesday, July 7, 2015, 2:00 p.m. EDT
Anticipated Award Notification:     September 2015

*Dates may change

There are two stages to the application process:

    1. Letters of Intent
    2. Proposals

An application for the Transformational Research Program requires a Letter of Intent, and applicants with high potential projects will be invited to submit a Proposal in late April 2015. Proposal instructions and feedback from our scientific review committee will be forwarded along with the invitation.

Request for Applications (RFA)

Program Details

Letter of Intent

A sample of the Proposal template is available by clicking here. Please note that the format and questions in the Proposal template are subject to change before the Proposal invitations so the template should be used only as an indicator of the expectations at the Proposal stage.

Program Information Session

To join the interactive information session conference call (Tuesday, February 3, 2015, 1:00 p.m. EST) please register here.

The Institute welcomes inquiries about this request for applications or any of our other funding opportunities. We would be pleased to hear from you at either or 416-935-4056.